Enhancement of solubility of aceclofenac by using different solubilization technique

Abstract

The objective of present research is to explore the application of different solubilization technique in the water- insoluble drugs and to reduce concentration of hydrotropic agent produce its own toxicity. In case of synergistic effect in solubility due mixing of hydrotropic agent , say,  the toxic level of individual can further be lowered because still less concentration of the hydrotropic agents shall be sufficient for a desired enhancement in solubility.