Investigation of wound healing activity of Malvastrum tricuspidatum syn Malvastrum coromandelianum on experimental animals

Abstract

Effects of topical administration of ethanolic extract of Malvastrum Tricuspidatum ointment was studied respectively on two types of wound models in wistar rats, (i) the incision and (ii) the dead space wound model. The ointment of the ethanolic extract of Malvastrum Tricuspidatum produced significant response in both of the wound types tested. In the incision model the extract treated wounds were found to epithelialise faster and the rate of wound contraction was higher, as compared to control wounds. The extract facilitates the healing process as evidenced by increase in the tensile strength in the incision model.