Anti-ulcer activity of Phyllanthus Niruri and Opuntia Ficus indica plant extract

Abstract

The present investigation carried out to study the anti-ulcer of opuntia
ficus indica fruit extract and phyllanthus Niruri herb extract using two
ulcer models Ethanol induced, and Pylorus ligation plus aspirin induced
models.Effect of various doses of Opuntia ficus indica and Phyllanthus
Niruri extract were studied on gastric secretion and gastric ulcers in
Pylorus ligation plus aspirin induced and on ethanol- induced gastric
mucosal injury in rats. The reduction in ulcer index in both the models
along with reduction in volume and total acidity, proved the anti ulcer
activity of opuntia ficus indica fruit extract and phyllanthus Niruri herb
extract. Thus it can be concluded that both plant possesses anti-ulcer
activity, which can be attributed to its anti-oxidant mechanism of action