Phytochemical analysis and antibacterial potential of Cardiospermum halicacabum Linn. (Sapindaceae)

Abstract

Methanolic stem extract of Cardiospermum halicacabum was examined for their phytochemical and antibacterial properties. The preliminary phytochemical screening of methanolic extract of Cardiospermum halicacabum showed the presence of bioactive components like Alkaloids, Flavonoids, Saponins, Tannins and Glycosides was absent in the plant extract. The methanolic stem extracts of Cardiospermum halicacabum was evaluated for antibacterial activity against medically important bacteria viz. Staphylococcus aureus, Bacillus subtilis, Esherichia coli, Klebsialla pnuemoniae  and  Proteus vulgaris. The in vitro antibacterial activity was performed by agar disc diffusion method. Among this Staphylococcus aureus and Bacillus subtilis showed the high zone of inhibition activity (18 ± 0.057 and 17 ± 1.5) and also showed lesser activity against the control (Ampicilin). It is concluded that the plant studied might be a good antibacterial source.