Anti-microbial studies of aqueous, methanolic and saponins extract of leaf of Ziziphus mauritiana on human vaginal pathogens causing UTI infection

Abstract

Preliminary phytochemical screening of the leaves extract of Zizyphus mauritiana revealed the presence of alkaloids, flavonoids, glycosides, saponins. The aqueous, methanolic and saponin extracts of Zizyphus mauritiana leafs has been screened for antimicrobial activities against some human vaginal pathogens Staphylococcus aureus, Pseudomonas aeruginosa, streptococcus facecalis, klebsiella pneumoniae, Escherichia coli, Enterobacter faecalis, Enterobacter faecium and Proteus mirabilis isolated from patient samples. Extracts were found to produce significant inhibition against all the pathogens. Saponin extract were observed to be more active than methanolic and aqueous fraction. Extracts are found to be more active against Enterobacter faecalis, Enterobacter faecium, Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus.