Review on Gastroretentive Drug Delivery System

Abstract

The oral delivery in English way was the very popular method, due to the ready taking of medicine and administration process. After oral administration of a drug, the process of its bioavailability being influenced by its stay in stomach are imperative. Lately, gastroretentive drug delivery systems (GRDDS) have been extensively used for drugs with a narrow absorption window, an inability to formulate the dose at high pH due to decreased stability and increasing solubility at low pH level Such drugs are the part of the design of medicine system that keeps for a while in the stomach and upon release of its active components causes the desired effect in the stomach. Achieving the desired result of gastric retention of drugs may be done through the use of agents of effervescence, mucoadhesive polymers, magnetic matter, bouncy enhancing carriers, along with a method which is effective in forming plug-like substances that are resistant to emptying of the stomach. Such conclusion records a concise viewpoint about the essential attributes of the latest individually addressed procedures on GRDDS.