Shilpi Gautam,Vishal Dubey*, Alka Maral and Shweta Sahu
Keywords:
Analgesic, Chronic pain, Inflammation, Analgesiometer, Plethysmometer.Abstract
Pain is an uncomfortable sensation triggered by the nervous system in response to tissue damage or other body damage. It can be dull, achy, shooting, burning, orpins-and-needles. Pain is tied to emotional, psychological, and cognitive factors and can be categorized into acute, chronic, referred, cancer, neuropathic, and visceral pain. Acute pain is experienced rapidly in response to disease or injury, while chronic pain lasts more than three months. Referred pain originates in one part of the body but is felt in another. Cancer pain is caused by nerve irritation caused by malignancy, neuropathic pain is caused by damage to the nervous system, and visceral pain is caused by problems with internal organs. Symptoms may include depression, flu-like symptoms, in ability to concentrate, muscle spasms, sleep disturbances, and un expected weight loss. Serious symptoms may indicate a life-threatening condition, such as a heart attack. Pain can be caused by a variety of diseases, disorders, and conditions, including inflammatory syndromes, malignancy, trauma, and infection.