In-vitro evaluation of Antibacterial and Antioxidant activity of ethanolic extract of Leucas aspera roots and leaves

Abstract

There is a currently worldwide upsurge in the use of herbal preparations
and active ingredients of medicinal plant in health care. This is
particularly true in the rural areas of Asian countries where herbal
medicines are the only choice for treating human ailments. Present study
reveals the data of in-vitro antibacterial and antioxidant activity of
ethanolic and chloroform extracts of roots and leaves of Leucas aspera
against the selected bacterial strains. Among all the extracts, ethanolic
extract showed greater activity with a zone of inhibition (by disc
diffusion assay) ranging from 6.5mm to 19mm. Ethanol extract
of Leucas aspera exhibited better antibacterial activity with IC50 value
range 17.95-50mg/ml when compared with chloroform extract. The
antioxidant activity stable 2,2-diphenyl-1-picrylhydrazyl-hydrate (DPPH
assay) of ethanolic extract of Leucas aspera showed the highest
antioxidant properties among all.