Investigation of Anti-diabetic Activity of aerial part of Rivea hypocrateriformis in Dexamethasone iinduced iDiabetes in Expermental animal
Keywords:
Dexamathasone, Plant extractAbstract
The idifferent iextracts iwere iprepared iand ievaluated ifor invivo iantidiabetic iactivity iby iusing iDexamethsone iinduced idiabetes imodel. The idecreased iin iweight iof iliver, ikidney iand ipancreas iafter ithe itreatment iwith iEERH imay ibe idue ito iprevention iof iinflammation, inecrosis iand iinfiltration iof iMNC idue ito ithe ioxidative istress iinduced iby idexamethasone. iThe iprotection iagainst ithe ihistopathological iinjury iof ipancreas, ias ievident ifrom ithe idecrease iinflammation, inecrosis iand iinfiltration iof iMNC iin ipancreatic itissue, ialso irevealed ithe iantioxidant ipotential iof i iEERH. iFurthermore, idecreased ibilirubin, iSGOT iand iSGPT ilevels isuggested ithat i iEERH iwere ieffectively iprotected ithe iliver iinjury idue ito ithe ioxidative istress iinduced iby idexamethasone.