Anti-inflammatory activity of hydroalcoholic extract of Quisqualis indica Linn. flower in rats

Abstract

Inflammation plays an important role in various diseases with high prevalence within populations such as rheumatoid arthritis, atherosclerosis and asthma. The aim of the present context to evaluated to the anti-inflammatory activity of hydroalcoholic extract of Quisqualis indica in wistar rats. It’s also known as Rangoon creeper or, madhumalati. The anti inflammatory activity was test using acute inflammatory models like; acetic acid-induced vascular permeability and chronic models like; cotton-pellet induced granuloma. Oral administration of the extract at the doses 100 and 150 mg/kg b.w. exhibited dose dependent and significant anti-inflammatory activity in acute (acetic acid-induced vascular permeability, p< 0.0001) and chronic (cotton pellet granuloma < 0.0001) Hence, present investigation established some pharmacological evidences to support the folklore claim that Quisqualis indica L. is use as anti-inflammatory agent.