Alteration in Serum Protein Profile in White Leg Horn Chicks with Experimental different doses of infection of Ascaridia galli

Abstract

The enteric nematode parasite Ascaridia galli modulate the immune system, of the hosts and eventually leads to malnutrition in the chicks which eventually results in the decreased return of products derived from poultry. The accurate interpretation of avian plasma proteins and the dramatic changes in protein fraction are important events in several diseases and may help in procuring a diagnosis .The present work was carried out to investigate the immunological alteration of serum protein profiles, induced along with different doses of A. galli infective eggs. The albumin concentration was found to be highly significantly (p<0.005) decreased in comparison to control group. The statistical analysis revealed highly significant (p<0.005) fall in IgA¹ antibodies as compared to the control group. The IgA² antibodies were found to be significantly (p<0.005) increased as compared to control group, depicting increased humoral immune response. The concentration of beta globulins were observed to be significantly (p<0.005) decreased as compared to control group. The IgG antibodies showed a significant (p<0.005) elevation in humoral immunity as compared to control group. The possible influence of the parasite induced alteration in immune responses in WLH Chicks is discussed in this paper.