Hematopoietic and modulatory effects of leaf extract of Annona muricata on Male adults rabbits

Abstract

Annona muricata L. (Magnoliales: Annonaceae) is a tropical plant species known for its edible fruit which has some medicinal merits, but also some toxicological effects. The present study was undertaken to evaluate the potential effects of A. muricata on hematopoietic and hematological parameters. Tenth rabbits were randomly divided into two equal groups (each group five rabbits). The first group was used as a control. The second group was used to study the effect of A. muricata L. (100 mg/kg body weight) for six weeks. Results indicated that treatment with A. muricata were not caused significant effect on packed cell volume (PCV), hemoglobin (Hb), mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC). A. muricata caused increased in the number of PLT compared with control group. In concluded, clinical studies are necessary to support the therapeutic potential of this plant.