Microbubble and its applications

Abstract

This review focuses on the characteristics of microbubbles that give them therapeutic properties and some important aspects of ultrasound parameters that are known to influence microbubbles-mediated drug delivery. In addition, current studies involving this novel therapeutic application of microbubbles will be discussed the microbubbles as drug carriers have an average size less than that of red blood cells .They are capable of penetrating even into the small blood capillaries and releasing drug and genes under the action of ultrasound field. Targeting ligands are attached to the surface of the microbubbles (i.e. targeted-microbubbles). Microbubbles dispersion method was investigated to improve oxygen transfer at low agitation rates and thus reduce power consumption and shear stress on the microorganisms. Myocardial contrast echocardiography is rapidly becoming a technique that can be utilized with intravenous with intravenous Microbubbles to detect myocardial perfusion abnormalities during stress echocardiography. Microbubbles destruction has been proposed as an innovative method for noninvasive delivering of drugs and genes to different tissues. Conventional flotation assisted with microbubbles (30–100 μm) finds application in the recovery of fine mineral particles (b13 μm) and flotation with these fine bubbles is being used as a solid/liquid separation to remove pollutants. Microbubble having boost utilization in formation of biofuel.Thus microbubbles having various applications in various fields.