Formulation and Evaluation of Matrix Tablets of Salbutamol Sulphate with reference to effects of Polymers

Abstract

Salbutamol sulphate is an antiasthamatic and bronchodilator agent, with half life of 1.6 hours and requires multiple daily doses to maintain adequate plasma concentrations. The objective of this present study is to develop a sustained release tablet of salbutamol sulphate which releases the drug in a sustained manner over a period, by using different polymers. The drug was formulated and evaluated as per standard procedure and it was found that F6 formulation gives optimum results.