Review on Emulgel: A Promising Formulation for Antifungal Drug for the treatment of Seborrheic dermatitis

Abstract

This review aims to demonstrate the effects and advantages of emulgel-containing antifungal medicines and suggest a technique for administering them. Because fungal infections such as seborrheic dermatitis are the most frequent global skin health concern, topical fungal medication is usually suggested due to its specific therapy and fewer adverse effects. Emulgel is one such topical medication delivery administration that combines emulsion and gel features and features a dual-release control system. Emulgel is a thermodynamically stable formulation with low interfacial tension derived from the combination of a surfactant and a co-surfactant. Emulgel gives improved stability, loading capacity, penetrability, and controlled drug release with a short half-life. The main objective of emulgel is to administer hydrophobic drugs through the skin so that through the skin, allowing a hydrophobic moiety to benefit from the special features of gels. Many medications in the antibacterial, antiviral, and nonsteroidal anti-inflammatory categories are now being researched for topical delivery via emulgel formulation, and a few are already on the market. Because of the numerous dermatological benefits offered by the emulgel formulation, it is a benefit in the derma care and cosmetology fields, as well as in enhancing patient compliance. This review summarizes new advanced approaches used in topical carriers to enhance antifungal drug clinical outcomes. Other parameters include pH, rheology, particle size, zeta potential, drug content, skin irritation test, in-vitro and in-vivo tests, and other properties of the prepared formulation and evaluation.