Accumulation of lead and cadmium in the organs and tissues of albino rat

Abstract

Lead and cadmium are trace metals which accumulate in the body and are extremely toxic in living organisms. The objective of the present study is to determine the accumulation of heavy metals Lead (Pb) and Cadmium (Cd) in different organs and tissues of Albino rat. The experimental animal was exposed to Pb and Cd at sub lethal concentration. The elements of Pb, and Cd were assayed by using shimadzu AA 6300 atomic adsorption spectrophotometry and the results were given as µg/g dry wt. The high level heavy metal accumulation was found to be in liver. The order of heavy metal accumulation in liver was Cd > Pb, and in kidney and tissues Pb > Cd. The results were statistically significant at p< 0.001.The accumulation of lead and cadmium was significantly high in tissues