Effect of Ethanolic extract of Michelia champaka Linn. on the Physical characteristic of pellet

Abstract

Indian medicinal plants are used as ancient style of providing helps too many ailments. Presently, variant peoples are looking on healthful plants for his or her primary health care wishes. Michelia champaca L. belonging to family Magnoliaceae commonly known as Svarna champa, a tall handsome tree with yellow fragrant blossoms.It is commonly used by many traditional herbal preparations. Being it's a vital healthful plant in Indian medication this are supposed to vary medical specialty activities like antipyretic, antifertility, analgesic, anti-inflammatory, antihyperglycemic, antiulcer, antimicrobial, antioxidant and wound healing activities. The aim of this study is to formulate ethanolic extract of Michelia champaka L. into a solid dosage form. Pelletization was developed to formulate the extract. The formula was prepared using various ratios of extract with 30 % PVP as a binder and MCC as a filler.The influence of extract concentration was studied on the pellet characteristics. Pellet was prepared by extrusion-spheronization technique. In order to produce pellet with optimum diameter, the moisture of the extrudates and speed of spheronizer was mantained properly. In particular for flow property, all pellets containing more than 5% of Michelia champaka extract were found to be better than blank pellets. The study finally concluded that  the presence of extract in the pellet formulas improved the physical characteristic of pellet. The self binding property of the extract is suggested as a key parameter for this improvement.