Advancements in Novel Drug Delivery Systems: A Comprehensive Review

Abstract

The field of drug delivery systems has witnessed significant advancements in recent years, driven by the need for more effective and targeted therapies. Novel drug delivery systems (NDDS) offer innovative solutions to overcome the limitations of conventional drug formulations, including poor bioavailability, off-target effects, and low patient compliance. This comprehensive review provides an overview of recent developments in NDDS, including nanoparticle-based systems, liposomes, micelles, hydrogels, and transdermal delivery systems. The review discusses key strategies employed in NDDS, such as targeted delivery, controlled release, and stimuli-responsive formulations, as well as their applications in various disease areas, including cancer, infectious diseases, and chronic conditions. Additionally, regulatory considerations, challenges, and future directions in the field of NDDS are explored, highlighting the potential of these technologies to transform drug therapy and improve patient outcomes.