A Review on Nanosponges: A versatile Profile for Novel Drug Delivery

Abstract

Effective drug delivery at a targeted site had given the possibility to perform the precise function to control the release rates and have a better compliance on the health care system but the chemistry possessing complex form had made conditions complicated. But the invention of nanosponges has given a significant approach toward solving this problem. Nanosponges are tiny sponges having size of about a virus and can be filled with variety of drugs. This sponges can circulate around the body until interact with specific target site and stick on surface and start releasing drug in a controlled manner. Some cyclodextrins based nanosponges proposed nanodelivery system and form porous insoluble nanoparticle having crystalline and amorphous nature. Important characteristic of these sponges is their solubility in aqueous form and give a effect to the drugs with poor solubility. This review is focusing on the preparation methods, applications of nanosponges in the field of drug delivery.