Evaluation of phytochemical constituents and In-vitro antibacterial activity of Synadium grantii

Abstract

In this study we investigated phytochemical screening and In-vitro antibacterial activity of hexane, ethyl acetate, ethanol (70%v/v) and methanol extracts of Synadium grantii. The results were revealed the presence of steroids, terpinoides, glycosides, tannins, alkaloids, phenols and carbohydrates but the all extracts are do not contain saponins, flavanoids, quinines, amino acids and oils.. The selected plant extracts were produced concentration dependent zone of inhibition against tested bacterial strains. The extracts showed more activity against gram negative organisms than gram positive organisms. The extracts showed better activity at highest concentrations i.e. at 600 and 1200 µg/100µl. Among the four types of Synadium grantii extracts, the ethyl acetate extract showed better activity than remaining extracts at 1200 µg concentrations against gram negative bacteria.