Diabetic Wound Healing Potential of Eclipta alba gel in diabetic rodent model

Abstract

The present study provides a scientific evaluation for the diabetic wound healing potential of herbal gel of
Eclipta.alba (Linn) Hassk, family Asteraceae, grow as a common in areas of upper gangetic plains , in pasture lands,
roadside in chhota Nagpur ,all districts of Bihar and Orissa,Punjab,Western India and South India. Diabetes mellitus
(DM) is a fast growing epidemic throughout the world. Diabetes is a chronic disease characterized by high level of
glucose in the blood. wound healing become challenging position to biomedical sciences when associated with
diabetic people.The herbal products are more precious in both prophylaxis as well as curative in delayed diabetic
wound healing activity of methanolic powder extract gel and hydro alcoholic extract gel of Eclipta alba in alloxan
(120mg/kg i.p.) inducd diabetic rats. A wound of 1cm incision was made on ventral side of diabetic male wister rats.
Two different gel of Eclipta.alba are applied on wound b.i.d.for 15 days .The initial and final fasting serum glucose
level was estimated to confirm the disease state. The plant Eclipta.alba Hassk (Asteraceae) having important role in
traditional Ayurvedic, Unani systems of holistic health and herbal medicine of the east.eclipta.alba Hassk is
reported to possess hepatoprotective, antimicrobial, anti inflammatory, analgesic, immunomodulatory , deobstruent,
antiviral and promoter for blackening and growth of hair .Important source of chemicals is Wedelolactone,
demethylwedelolactone exhibit anti hepatotoxic activities.