Formulation and Evaluation of Herbal Cream containing alcoholic extract of Sauromatum guttatum (Wall.) Schott for the treatment of Fungal infection

Abstract

Sauromatum guttatum (Wall.) family Araceae, known as bhasamkand is
an perennial herb. The herb grows widely during rainy season. The plant
is widely distributed in the moist area of Punjab plains, Upper Gangetic
plain, Dehradun, Budelkhand, Chota Nagpur, Tirhut, Konkan, Deccan
and Madhya Pradesh. Tubers are the main part of the plant, used in
treatment of various ailments. Present investigation deals with
formulation of herbal cream containing alcoholic extract of Sauromatum
guttatum (Wall.) tuber. Seven different batches F1 to F7 were formulated
using different proportion of excipients. The formulated batches were
evaluated for their physical characteristics, spreadibility, drug content,
drug release and stability studies. The result indicates that the
formulation code, F5 is showing better results as compared to other
formulation codes. Anti-fungal activity of optimized herbal cream was
determined and was reported in present paper, also further clinical
efficacy required to establish for optimized formulation.