Antianxiety effect of ethanolic extract of leaves of Ipomea mauritiana in swiss albino mice

Abstract

Ipomea mauritiana commonly known as giant potato belonging to the family convolvulaceae. The objective of this study was to evaluate antianxiety activity of ethanol extract of the leaf of Ipomea mauritiana in swiss albino mice. swiss albino mice were divided into four groups (n=6)group I and group II received normal saline and diazepam respectively. while group III and group IV received Ipomea mauritiana orally at dose 200mg/kg and 400mg/kg body weight. Anti-anxiety was assessed by using elevated plus maze (EPM) and light and dark model methods. The ethanolic extract exhibit anxiolytic effect in experimental mice. So it is supports the use of Ipomea mauritiana as anxiolytic agents. Further investigation should be made to elucidate the active constituent of responsible for the activity.