Evaluation of Antidepressant activity of Crossandra infundibuliformis

Abstract

As per report 21% of world’s population has been affected by depressive disorder which is a prevalent psychiatric disorder. The presently using drugs can impose a variety of side-effects including cardiac toxicity, hypopiesia, sexual dysfunction, body weight gain, and sleep disorder. During the last decade, there is a growing interest in the therapeutic effects of natural products on mental disorders. Antidepressant activity of extract of Crossandra infundibuliformis was investigated by using Forced swimming test (FST) and Tail suspension test (TST) models. Imipramine were used as reference standards. It has been observed from our study that extract showed significant reduction in immobility in tail suspension and forced swim model of depression.