Instamodel in the development and evaluation of diclofenac sodium matrix tablet and its effects of release of drug from matrix dosage forms

Abstract

Instamodel is a polymer that is used in the formulation development of matrix based tablet as sustained release drug delivery system includes all the dosage forms formulated to retard the release of the therapeutic agent such that its appearance in the systemic circulation is delayed and/or prolonged and its plasma profile is sustained in duration the onset of drugs pharmacologic action is often delayed and the duration of drugs therapeutic effects is sustained. Now a day, matrix and micro encapsulation is the most frequently employed method of producing sustained release dosage forms. Over the few decades’ enormous progress has been made in developing these two technologies and applying it to diverse field of medical and other usage. In the following article mode formulation and various other evaluation parameter are discussed and finally shown the effect of their concentration on the drug release profile.