Synthesis and antibacterial activity of new schiff’s bases

Abstract

Five novel schiff bases have been prepared from 2-Amino-4-(4-acetanilido) thiazole and substituted aromatic aldehyde to form a number of potentially biologically active Schiff bases (SA₁-SA₅). The structure of all these compounds have been established on the bases of analytical and spectral data compounds SA₁-SA₅ are comparable with standard drug ampicillin against s. aureus and E.coli. Compounds SA_2, and SA₅  shows good activity as compared to standard drug.