Studies on evaluation of anti-inflammatory activity of Pterospermum acerifalium (L.) against carrageenan induced paw edema

Abstract

Inflammation is a process in which the body's white blood cells and chemicals help protect us from infection and foreign substances such as bacteria and viruses. In some diseases, however, the body's defense system (immune system) triggers an inflammatory response when there are no foreign substances to fight off. Ethanolic extract of Clerodendrum serratum Linn., leaves were evaluated for anti-inflammatory activity. Extract did not show any signs of toxicity at the dose of 1000 mg/kg per organism (p.o.). From the acute toxicity test we selected two doses (50 and 100mg/kg) for subsequent pharmacological study.