Stability Indicating Assay Method Development and Validation for Ondansetron hydrochloride and Prantoprazole sodium in Bulk and Pharmacetical Dosage Form

Abstract

This thesis presents the development and validation of a stability-indicating assay method for the simultaneous estimation of ondansetron hydrochloride and pantoprazole sodium in bulk and pharmaceutical dosage forms, utilizing high-performance liquid chromatography (HPLC). The method development focused on optimizing the chromatographic conditions, which included the selection of an appropriate column, mobile phase composition, flow rate, and detection wavelength. . This validated method is suitable for routine quality control and stability testing of ondansetron hydrochloride and pantoprazole sodium in bulk and pharmaceutical formulations.