Antidiabetic Activity of Some Selected Indian plants in Food Induced Type 2 Diabetes

Abstract

Type 2 diabetes usually begins in the middle age or after 40 years. It is
not uncommon to come across the development of diabetes in third
decade itself in our country. Diabetes mellitus is a complex and a
multifaactorial group of disorders that disturbs the metabolism of
carbohydrates, fat and protein. The chronic hyperglycemia of diabetes is
associated with long term damage, dysfunction and failure of various
organs. Diabetic complications arise partly from glycosylation damage to
structural and functional proteins and reflect chronic failure to maintain
blood glucose homeostasis. Some plants of genus Spermacoce and Sida
have received great attention recently due to its long history of use in
oriental countries and its medicinal values for the treatment of many
diseases such as stomachaches, inflammation, arthritis, gastroenteric disorders, tumors and lymphatic disorders. In the current study, methanolic
extract of Genus Spermacoce and Sida Plants evaluated for their
antidiabetic effects in fructose fed rats. Present study has shown a
significant glucose level control in blood.