Formulation and Evaluation of Orchis laxiflora L. Antibacterial Mouthwash

Abstract

Mouthwashes are aqueous topical medicines that clean the interior of the mouth by washing and gargling. There are a variety of mouthwashes with a variety of active ingredients available over the counter and by prescription that can be used as an adjunct to help with the multifactorial management of complex oral conditions like halitosis, gingivitis, periodontal disease, oral mucositis, and even xerostomia, among others. Clove is the most commonly applied directly to the gums for toothache, pain control during work and other dental related issues. We have developed a mouthwash with some common food materials and herbs and which can replace costly chemicals like alcohol, coloring agents and preservatives making our mouthwash economically more viable than commercial mouthwash. The anti-inflammatory and anti-infectious properties of Neem make it a powerful treatment for gum disease. The results of this study indicate that the existence of compounds such as glycosides, terpenoids, flavenoids and saponins that can be responsible for the anti-bacterial efficacy of extracts and poly herbal mouthwash rinse against these microorganisms that are known to be mostly responsible for oral cavity bacterial infection.