Transdermal Drug Delivery Patches: Overview of Systemic Review

Abstract

Transdermal patches are now widely used as cosmetic, topical and trans dermal delivery system. A transdermal patches is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the blood stream. This promotes healing to an injured area of the body. An advantage of a trans dermal drug delivery route over the types of medication delivery such as topical, intravenous, intramuscular, etc. that the patch provide a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layer of medication embedded in the adhesive. Transdermal drug deliver offers controlled release of the drug into the patient, it enables a steady blood level profile resulting in reduced systemic side effect and sometime, improved efficacy over other dosage forms. The main objective of trans dermal drug delivery system is to deliver drug into systemic circulation through skin at predetermined rate with minimal inter and intra patient variations.