Development and Validation of Bio-analytical method for Dapagliflozin in human plasma by LC-MS/MS

Abstract

When samples are biological fluids such as plasma, serum or urine, this technique is described as Bioanalytical sample preparation. This technique is used to clean up a sample before analysis and/or to concentrate a sample to improve its detection. In the present work development and validation of Bioanalytical method determination of drug from dosage form by HPLC and biologicalmatrices by LC-MS/MS. In this paper Bioanalytical technique for the quantitation of CAN, DAP and OND in human plasma along with stability studies by LC-MS/MS method.