Evaluation of Analgesic activity of various extract of Michelia champaca Linn.

Abstract

The present investigation reveals that the ethanolic extract (EEMCSB) of M. champaca exhibit its maximum analgesic activity of 74.79%, by hot plate method at the given dose of 500mg/kg, followed by 71.28% EEMCSB at the dose 250 mg/kg, and it was significant when compared with control and standard group.The aqueous extract showed a moderate analgesic activity of AEMCSB 35.48 % at the dose 500 mg/kg and AEMCSB 32.13 % at the dose 250 mg/kg when compared with control and standard group. Study reveals that the ethanolic extract of M. champaca exhibit its maximum analgesic activity of by tail flick method at the given dose of 500mg/kg, and it was significant when compared with control and standard group.The aqueous extract showed a moderate analgesic activity when compared with control and standard group. Hence, from the present work it was concluded that the selected medicinal plants M. chmapaca Linn. of Indian origin possess optimum analgesic activity which will claims their folk-lore uses as mentioned in traditional system of medicine.