Formulation Development and Evaluation of Acyclovir Loaded Nanoemulsion

Abstract

This work deals with the investigations carried out on the preparation and characterization of oil-in water nanoemulsion containing acyclovir with minimum surfactant concentration that could improve its solubility and oral bioavailability. On the basis of above study it was concluded that the solubility in the oils, surfactants and co surfactants like Span 40, Castor Oil, Oleic acid, PEG 400, Ethanol was found to be soluble and Tween 20, Tween 80 and Sunflower Oil was found to be Slightly soluble for the nanoemulsion preparation of acyclovir.