Hepatoprotective activity of alcoholic and aqueous extracts of leaves of Anisochilus carnosus (Linn.)Wall

Abstract

The aim of the research is to find out new hepato-protective drug from indigenous plant which are potent and non-toxic or minimal toxic and to investigate the hepato-protective activity of alcoholic and aqueous extract of leaves of Anisochilus Carnosus (L )Wall  against Rifampicin induced hepatotoxicity. Leaf  powder of  Anisochilus Carnosus (L) Wall was successively extracted with petroleum ether, alcohol and aqueous. Preliminary phytochemical tests were done and the LD50 values for both  aqueous and alcohol extract determined. The hepatoprotective activity of the alcoholic extract (400 mg/kg P.O.) and aqueous extract (400mg/kg P.O.) were assessed in Rifampicin induced hepato toxicity in rats