Hepato-protective activity of Enicostemma axillare in paracetamol induced hepato-toxicity in albino rats

Abstract

The present study was conducted to evaluate the hepato-protective activity of water extract of aerial parts of Enicostemma axillare in paracetamol-induced hepatotoxicity in albino rats. Silymarin (200mg/kg) was given as reference standard. The water  extract of arial parts of Enicostemma axillare  have shown very significant hepatoprotection against paracetamol -induced hepatotoxicity in albino rats in reducing serum total bilirubin, SALP, SGPT , SGOT levels and liver homogenates LPO, SOD, CAT, GPX, GST and GSH levels.